Reducing infection risk is crucial for the prevention of complications and the promotion of faster wound healing.[4,5]
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Effective wound care
From biofilm to better healing: Reducing the burden of chronic wounds
While biofilm on wounds remains a critical barrier to recovery1, reducing the burden of wound infection, implementing prevention strategies, and accelerating wound healing are crucial components of clinical practice.[2]
Today, effective and modern wound care means more than just targeting biofilm prevention and treatment. It means delivering measurable outcomes: fewer dressing changes, less pain, and faster return to function. As part of this, understanding how to optimally conduct therapeutic wound cleansing is essential to improving patient care.[3]
United in Care with Prontosan®
The solution that helps cleanse, debride and protect against infection.
Reduced infection risk
Prontosan® helps lower the risk of infections, providing a safer healing environment for patients.[6-9]
Fewer dressing changes
Reducing the frecuency of dressing changes increases patient comfort and save costs.[10-11]
The use of Prontosan® can lead to a reduction in the frequency of dressing changes, making wound management more convenient.[12]
A quick recovery
Faster recovery times allow patients to return to their daily activities sooner, enhancing overall well-being.
Studies show that chronic wounds treated with Prontosan® heal significantly faster than with saline alone.[7,13,14,15]
Less pain and odor
Managing pain and odor improves patient comfort and quality of life.
Prontosan® helps reduces wound-related pain[16-19] and odor[16], improving patient mobility and socializing.
Clean wounds
Maintaining a clean wound is vital for preventing infections and promoting healthy tissue regeneration.
Prontosan® removes debris, slough, and biofilm, ensuring a clean wound bed which is essential for healing.[12,13,16,17,18,20]
What does your hospital appreciate?
Cost savings
Cost-effective treatments are essential for healthcare systems to manage resources efficiently.
Prontosan® helps reduce overall healthcare expenses by preventing infections and shortening healing times.[21,22]
Patients appreciate your care.
You appreciate the results from Prontosan®.
Improved recovery
"I see a difference every day".
A healing journey with Prontosan®.
Effective wound care does more than protect against biofilm — it plays a key role in helping patients heal faster, feel more comfortable, and regain their independence. When wounds are cleaned thoroughly and consistently, the risk of complications decreases, recovery times improve, and patients can return to their daily lives with greater confidence and less reliance on ongoing care.
Prontosan® Wound Bed Preparation System
Achieve better therapeutic cleansing outcomes with the Prontosan® system
Wound bed preparation with the Prontosan® System mobilizes synergistic ingredients to perform a more effective cleansing than the use of saline or water alone.[6,7,16,23,24]
Learn more about our complete range of solutions
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warningReferences
- Percival, S. L. (2016). Importance of biofilm formation in surgical infection. Journal of Hospital Infection, 92(3), 222–227. https://doi.org/10.1016/j.jhin.2015.07.009
- Millán-Reyes, M.J.; Afanador-Restrepo, D.F.; Carcelén-Fraile, M.d.C.; Aibar-Almazán, A.; Sánchez-Alcalá, M.; Cano-Sánchez, J.; Mesas-Aróstegui, M.A.; Castellote-Caballero, Y. Reducing Infections and Improving Healing in Complex Wounds: A Systematic Review and Meta-Analysis. J. Clin. Med. 2025, 14, 3237. https://doi.org/10.3390/jcm14093237[1](https://www.mdpi.com/2077-0383/14/9/3237)
- International Wound Infection Institute (IWII) Therapeutic wound and skin cleansing: Clinical evidence and recommendations. Wounds International 2025.
- International Wound Infection Institute. Wound Infection in Clinical Practice: Principles of Best Practice. Wounds International; 2022.
- Phillips K. Sustaining Improved Patient Outcomes in the Reduction of Wound Infections. Wounds UK; 2025.
- Andriessen AE, Eberlein T. Assessment of a wound cleansing solution in the treatment of problem wounds. Wounds. 2008;20(6):171-5.
- Möller A, Kaehn K, Nolte A. Erfahrungen mit dem Einsatz polihexanidhaltiger Wundprodukte bei der Versorgung chronischer Wunden - Ergebnisse einer systematischen retrospektiven Untersuchung an 953 Patienten [Experiences in using polyhexanide containing wound products in the management of chronic wounds – results of a methodical and retrospective analysis of 953 cases.]. Wund Management. 2008:111-7. In German.
- Ciprandi G, Ramsay S, Budkevich L, Strack A, van Capellen P, Marathovouniotis N. A retrospective systematic data review on the use of a polihexanide-containing product on burns in children. J Tissue Viability. 2018;27(4):244-8.
- Kiefer J, Harati K, Müller-Seubert W, Fischer S, Ziegler B, Behr B, Gille J, Kneser U, Lehnhardt M, Daigeler A, Dragu A. Efficacy of a Gel Containing Polihexanide and Betaine in Deep Partial and Full Thickness Burns Requiring Split-thickness Skin Grafts: A Noncomparative Clinical Study. J Burn Care Res. 2018 Aug 17;39(5):685-693.
- Upton D, Solowiej K. Painful Dressing Changes for Chronic Wounds: Assessment and Management. Journal of Wound Care; 2012 .
- Kirkcaldy AJ, Wilson M, Cooper R, Baxter SK, Campbell F. Strategies for Reducing Pain at Dressing Change in Chronic Wounds: Protocol for a Mapping Review. BMJ Open; 2023.
- Atkin L, et al. Wound bed preparation: a case series using polyhexanide and betaine solution and gel-a UK perspective. J Wound Care. 2020 Jul 2;29(7):380-386.
- Bellingeri A, Falciani F, Traspedini P, Moscatelli A, Russo A, Tino G, Chiari P, Peghetti A. Effect of a wound cleansing solution on wound bed preparation and inflammation in chronic wounds: a single-blind RCT. J Wound Care. 2016 Mar;25(3):160, 162-6, 168.
- Valenzuela AR, Perucho NS. The effectiveness of a 0.1% polyhexanide gel. Rev Enferm. 2008;31(4):7-12.
- Eberlein T. Expert assessment: Expert assessment on the benefits of systematic application of Prontosan® solution in wound treatment with particular focus on cost-efficiency when compared to current standard treatment (saline/Ringer). 2006.
- Romanelli M, Dini V, Barbanera S, Bertone MS. Evaluation of the efficacy and tolerability of a solution containing propyl betaine and polihexanide for wound irrigation. Skin Pharmacol Physiol. 2010;23 Suppl:41-4. doi: 10.1159/000318266. Epub 2010 Sep 8.
- Durante CM, Greco A, Sidoli O, Maino C, Gallarini A, Ciprandi G. Evaluation of the effectiveness of a polyhexanide and propyl betaine-based gel in the treatment of chronic wounds. Minerva Chir. 2014 Oct;69(5):283-92
- Horrocks A. Prontosan wound irrigation and gel: management of chronic wounds. Br J Nurs. 2006 Dec 14-2007 Jan 10;15(22):1222, 1224-8.
- Ricci E. Cleansing versus tailored deep debridement, a fresh approach to wound cleansing: an Italian experience. J Wound Care. 2018 Aug 2;27(8):512-518.
- Bradbury S, Fletcher J. Prontosan made easy. Wounds international. 2011;2(2):1-6.
- Cooper DM, Bojke C, Ghosh P. Cost-Effectiveness of PHMB & betaine wound bed preparation compared with standard care in venous leg ulcers: A cost-utility analysis in the United Kingdom. J Tissue Viability. 2023 May;32(2):262-269.
- Gansen F, Hepworth C; Richardson S; Rice C; Davidson J, Frei T; Barth C. Polihexanide and Betaine (PSGX) Containing Solution Versus Saline for the Treatment of Leg Ulcers: A Comparative Cost Analysis Using Real-World Data From England. Value in Health (2024) 27:12 Supplement (S63-S64). Date of Publication: 1 Dec 2024, ISPOR.
- Oropallo, A., Rao, A. S., Del Pin, C., Ranire-Maguire, M., & Mathew, A. (2024). An objective comparative study of non-surgical cleansing techniques and cleanser types in bacterial burden management. International wound journal, 21(2), e14730.
- Davis SC, Harding A, Gil J, Parajon F, Valdes J, Solis M, Higa A. Effectiveness of a polyhexanide irrigation solution on methicillin-resistant Staphylococcus aureus biofilms in a porcine wound model. Int Wound J. 2017;14(6):937-44.
- International Wound Infection Institute (IWII) Therapeutic wound and skin cleansing: Clinical evidence and recommendations. Wounds International 2025.